New Covid variants under the microscope

From: POLITICO Future Pulse - Friday Oct 21,2022 06:01 pm
The ideas and innovators shaping health care
Oct 21, 2022 View in browser
 
Future Pulse

By Grace Scullion , Ben Leonard and Ruth Reader

WEEKEND READ

In this photo illustration, an at-home COVID-19 test by Abbott shows a positive result.

A Covid-19 test at the ready. | Photo Illustration by Scott Olson/Getty Images

There’s a new jumble of Covid variants on the loose: BQ.1, BQ.1.1, and XBB. It’s enough to make the heads of a pandemic-weary public spin.

Here’s what we know about them: The BQs are offshoots of the reigning BA.5 Omicron strain, which once made up nearly all Covid cases in the U.S. and is still responsible for nearly seven out of 10.

But infections with the new BQ variants have tripled in the past two weeks, according to CDC data.

“On paper, [BQ.1.1] looks like a virus that has probably, to date, the most ability to escape vaccine-induced immunity, as well as some antibody treatments,” said Andy Pekosz, a professor of microbiology at Johns Hopkins Bloomberg School of Public Health, in a Global News video.

Epidemiologists believe the latest booster, designed to target the Omicron strain and available to Americans aged 5 and up who’ve had their first two shots, will help stave off serious cases. But low vaccine uptake worries them. Only about 7 percent of eligible people have gotten the new jab.

"The bad news is that there’s a new variant that’s emerging and that has qualities or characteristics that could evade some of the interventions we have," said President Joe Biden’s chief medical adviser, Anthony Fauci, in an interview with CBS News. “The somewhat encouraging news is that it’s a BA.5 sublineage, so there are almost certainly going to be some cross-protection that you can boost up.”

And then there’s XBB, a variant highlighted as “the most antibody-evasive strain tested” in a study by researchers at Peking University. The variant has yet to appear on the CDC’s dashboard, but has been detected in the U.S. and 25 other countries. Cases in highly vaccinated Singapore, where the variant is dominant, are almost all mild or asymptomatic.

Why are we talking about variants again?

We’re in “ a new evolutionary phase in the pandemic,” wrote The Washington Post’s Carolyn Johnson. “To focus too much on any one possible variant is, many experts argue, missing the point. What matters is that all these new threats are accumulating mutations.”

The growing number of Covid attackers means a person with a diverse array of antibodies has the best chance of warding off serious illness, Stuart Ray, a professor of medicine at Johns Hopkins, told Future Pulse.

“The new bivalent booster increases the diversity of those antibodies – increasing the chances that they’ll bind to a newer variant,” Ray said.

Across the Atlantic: Rates of infection, hospitalization, intensive care admission and death from Covid are increasing in Europe, Forbes reported, perhaps foretelling another winter surge.

But the European Centre for Disease Prevention and Control reported that the death rate remained low, even as it is rising in 11 countries. Deaths also remain near pandemic lows in the U.S. and are declining.

Europeans’ updated booster rates are on par with Americans’, though Europeans are more likely to have received the previously recommended shots.

 

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TWEET STORM

Fox News host and Covid-19 vaccine skeptic Tucker Carlson sparked a firestorm when he tweeted a clip from his show claiming the CDC was going to make the Covid-19 vaccine mandatory for kids to go to school.

The problem: That’s not how it works. 

Vaccine requirements for schools are determined at the state or local level.

Most states do take into account the CDC’s recommendations, which now include the Covid vaccine, and cite them to justify their own school vaccine requirements. But states also don’t require all of the recommended shots, such as the annual flu vaccine or the HPV vaccination to prevent cervical cancer.

Carlson’s claim stemmed from votes CDC advisers took this week to add the Covid jabs to the federal Vaccines for Children Program, and to the agency’s recommended schedule of vaccines for children.

That sets the stage for the shots to be available for kids whose families can’t afford them, as POLITICO’S David Lim reported. And it will likely prompt states to consider whether they should add them to their required school lists, reported POLITICO's Lauren Gardner.

The response: Twitter slapped a label on Carlson’s tweet – his video had nearly two million views as of Thursday morning – but didn’t remove it.

Twitter label:

https://twitter.com/TuckerCarlson/status/1582534550651080706 | Twitter

The CDC also responded on Wednesday.

CDC tweet to Tucker Carlson:

Twitter

Some criticized the CDC for getting involved, saying the agency amplified his message. The Washington Post reported: “The CDC’s response drew criticism from public health experts, who said the agency did not explicitly rebuff Carlson’s claim or speak in plain language.”

Carlson’s rebuttal: The Fox host responded to the agency in a segment Wednesday night, accusing it of “lying.” Carlson cited several states’ school vaccine requirements that track the CDC’s recommended schedule, including Massachusetts , Tennessee , and Virginia .

On the ground: The only public school system in the United States to require Covid vaccination is in New Orleans, though it’s easy to opt out. Laws to require kids to get the shots to attend school are on hold in Los Angeles and Washington, D.C.

On the trail: The situation is becoming a campaign issue already.

John Craven tweet: Today @CDCgov's Advisory Committee on Immunization Practices voting on adding COVID vaccine to the childhood vaccination schedule🐠Important to note: This is not a *mandate* to attend school (as Tucker Carlson claimed); states determine thatBut it's becoming a campaign issue.

Twitter

And GOP governors, including Kay Ivey of Alabama, Bill Lee of Tennessee, Kim Reynolds of Iowa, Ron DeSantis of Florida, and Kevin Stitt of Oklahoma tweeted that they'd ignore the CDC's guidance in setting school vaccine requirements.

A tweet by Oklahoma GOP Gov. Kevin Stitt stating that he would not impose a Covid vaccine mandate for schoolchildren despite new CDC guidance suggesting that the vaccine be routinely administered.

Twitter

 

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